In mathematics, a Hadamard matrix, named after the French mathematician Jacques Hadamard, is a square matrix whose entries are either +1 or −1 and whose rows are mutually orthogonal. In geometric terms, this means that each pair of rows in a Hadamard matrix represents two perpendicular vectors, while in combinatorial terms, it means that each pair of rows has matching entries in exactly half of their columns and mismatched entries in the remaining columns. It is a consequence of this definition that the corresponding properties hold for columns as well as rows. The n-dimensional parallelotope spanned by the rows of an n×n Hadamard matrix has the maximum possible n-dimensional volume among parallelotopes spanned by vectors whose entries are bounded in absolute value by 1. Equivalently, a Hadamard matrix has maximal determinant among matrices with entries of absolute value less than or equal to 1 and so is an extremal solution of Hadamard's maximal determinant problem.

Certain Hadamard matrices can almost directly be used as an error-correcting code using a Hadamard code (generalized in Reed–Muller codes), and are also used in balanced repeated replication (BRR), used by statisticians to estimate the variance of a parameter estimator.